Syl wrote:

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Digger wrote:

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I've been taking this for a week and it's a bit of a game changer.   I have more energy and I'm sleeping better. 

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 Where do you buy it from ?

 

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 From the company named on the packet.  Longevity Box.

NAD+ is a central metabolic intermediate linked to many hallmarks of aging, and its levels decline with age, impacting energy, cell regeneration, and overall health.   Due to its importance in cellular processes and its decline with age, NAD+ is a focus of research in anti-aging and wellness. 

NAD+ is crucial for converting food into energy that cells can use. 

Digger wrote:

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Maddog wrote:

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Digger wrote:

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I've been taking this for a week and it's a bit of a game changer.   I have more energy and I'm sleeping better. 

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 Its banned here.

 

At least for now..

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 NMN is not NMNH.   There's a difference.

 

https://pmc.ncbi.nlm.nih.gov/articles/PMC7770224

 

Apparently this also lowers cholesterol - something big Pharma don't want.

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 It appears it's a different form of the same thing basically.

There seems to be some good research stating it helps with insulin uptake, inflammation and sleep. 

All problems associated with age. I'm surprised I haven't read or heard about it as I stay fairly informed on supplements..

Anonymous wrote:

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Maddog wrote:

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It doesn't matter what a woman looks like or weighs, if she can't do 10 push-ups, she's not in shape..

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 How many can you do?

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 On chest days I do 30, then a set of 25, then a set of 20..

I guess I could do 40 if I tried. 🤷

Vam wrote:

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I’ve been taking a daily anti-inflammatory Tumeric supplement for the last 20 years.

The one I get over here (called No-Dol) works even better than what I used to buy in London.

Happy to report I’ve never suffered with joint stiffness/inflammation.

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 I just throw some turmeric in several meals a week. It doesn't have a strong flavor, and I use a lot of spice in every thing, so it doesn't change the taste of my food. 

There are ways to help absorption. 

Vam wrote:

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jackb wrote:

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I stopped turmeric and replaced it with cardamom powder as 97% of turmeric gets pooped and peed out.
It doesn't get digested and make it to your blood stream.

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 You could be right, Jack. But are you saying tumeric tablets in a highly concentrated format doesn’t absorb well either?
 
I used to sometimes get achy back in the day, especially after horse riding. Started on tumeric - have rarely felt the slightest twinge since.

Again, anecdotally, a friend recently had some very severe pain in 2 of her fingers - she couldn’t straighten them! Her doc said it was osteoarthritis. I gave her a pack of No-Dol capsules to try. They started working for her within a week.

Anyway, just in case anyone’s interested, I checked, and see No-Dol is available in the UK. Make sure you get the pack that says ‘Curcuma’ (Spanish for tumeric). Here, they’re available over the counter at the chemists. 

https://www.naturitas.co.uk/p/supplements/collagens-and-cartilages/collagen/no-dol-30-capsules-esi?srsltid=AfmBOoohQLaOGSbMeNfHMbwT3aVBFpipeselCbFW-Jyl9xKRa0wViKLO

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 Lots of those supplements are mixed with some firm of pepper, which helps absorption.

I know a guy that just chokes down a teaspoon of the stuff. That's not a good way to do it. 

Vam wrote:

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jackb wrote:

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I stopped turmeric and replaced it with cardamom powder as 97% of turmeric gets pooped and peed out.
It doesn't get digested and make it to your blood stream.

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 You could be right, Jack. But are you saying tumeric tablets in a highly concentrated format doesn’t absorb well either?
 
I used to sometimes get achy back in the day, especially after horse riding. Started on tumeric - have rarely felt the slightest twinge since.

Again, anecdotally, a friend recently had some very severe pain in 2 of her fingers - she couldn’t straighten them! Her doc said it was osteoarthritis. I gave her a pack of No-Dol capsules to try. They started working for her within a week.

Anyway, just in case anyone’s interested, I checked, and see No-Dol is available in the UK. Make sure you get the pack that says ‘Curcuma’ (Spanish for tumeric). Here, they’re available over the counter at the chemists. 

https://www.naturitas.co.uk/p/supplements/collagens-and-cartilages/collagen/no-dol-30-capsules-esi?srsltid=AfmBOoohQLaOGSbMeNfHMbwT3aVBFpipeselCbFW-Jyl9xKRa0wViKLO

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 Powdered turmeric must be mixed with some kind of oil or fat.   Otherwise it does not get absorbed into the body.

Yes, it's true that turmeric has a low absorption rate, with only about 2-3% of the curcumin in turmeric actually being absorbed into the bloodstream. This is due to curcumin's poor bioavailability, meaning the body struggles to absorb and utilize it effectively. 

Here's a more detailed explanation:

Low Curcumin Content:

Turmeric powder contains a relatively small amount of curcumin, the active compound responsible for its potential health benefits, typically around 2-6% by weight. 

Poor Bioavailability:

Even though turmeric contains curcumin, the body doesn't absorb it well, with studies showing that only a small portion, around 2-3%, enters the bloodstream. 

Factors Affecting Absorption:

Several factors can impact curcumin absorption, including the form of turmeric (powder, extract, supplement), the presence of other substances (like black pepper), and individual differences in digestion. 

Strategies to Improve Absorption:

Curcumin Supplements: Some supplements are formulated to improve curcumin absorption, often by using specific delivery systems or combining it with other ingredients like black pepper (piperine). 

Fat-Soluble Nature: Curcumin is fat-soluble, meaning it dissolves better in fats. Consuming turmeric with a source of fat can enhance its absorption. 

Black Pepper: Piperine, a compound found in black pepper, can significantly increase curcumin absorption. 

Dosage:

To achieve the desired effects, higher doses of curcumin may be needed, which can be difficult to attain solely through dietary turmeric. 

Digger wrote:

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Syl wrote:

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Digger wrote:

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I've been taking this for a week and it's a bit of a game changer.   I have more energy and I'm sleeping better. 

---

 Where do you buy it from ?

 

---

 From the company named on the packet.  Longevity Box.

 

NAD+ is a central metabolic intermediate linked to many hallmarks of aging, and its levels decline with age, impacting energy, cell regeneration, and overall health.   Due to its importance in cellular processes and its decline with age, NAD+ is a focus of research in anti-aging and wellness. 

NAD+ is crucial for converting food into energy that cells can use. 

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 I ordered some, I can give it a go and see what happens.